The Biology
Following fertilisation, the single cell splits into two and then into four cells and so on. This process is known as Cell Division. First, cells copy their genetic information or “genes” and these are then shared equally between the two new cells. Genes are made of DNA and are located in the centre of the cell in the nucleus. During cell division they appear as finger-like structures called chromosomes.
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(above) Top cell is just about to divide , while the lower cell is dividing, separating its chromosomes (pink) equally into two groups.
Film Cedit: Jason Swedlow, University of Dundee
Images © Wellcome Images
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When development goes wrong
Mistakes in cell division can have major consequences. A well-known example of this is Down syndrome, where failure to segregate chromosomes equally into the two new cells during the production of sperm or eggs results in an embryo with an extra copy of chromosome 21.

Image © 2011 Trustees of Dartmouth College |
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Problems with cell division can occur in adults too. This can lead to diseases such as Cancer where cells divide without control and make mistakes in chromosome separation.
(picture) Left cell dividing correctly, but left cancer cell (right) has not separated chromosomes (light blue) equally between cells.
There are now many treatments available for cancer patients, including tumour removal by surgery, radiotherapy and chemotherapy.
Find out more:
Cancer Research UK funds researchers working on many different kinds of cancer. Studies range from investigation of fundamental biological processes whose malfunction causes cells to become cancerous, to trials for possible treatments for cancer.
Cancer Research UK
Down Syndrome Association
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Anaphase dress: Silk, mirrored paper, viscose jersey
The floating breastplate shows pairs of chromosomes pulling apart as a cell divides.
Red fringing is a reminder of the spindles along which the chromosomes are drawn.
Drawing
1997
Copyright Helen Storey
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